State Research Institute Centre for Innovative Medicine (IMC)
- Clinical practice begins in our laboratories.
- Visions of therapeutic and diagnostic strategies are transferred into clinically relevant knowledge and expertise.
Exosomes as potent therapeutic tools against neurodegenerative diseases
Exosomes derived from human stem cells are used in Parkinson’s disease model, as medicine. Now, good results are reached while treating Parkinson’s disease in animal model. It is planned that this technology will be developed till drug candidate.
Combined therapy technology for arthritis treatment
Many technologies are developed for various origin arthritis treatment and diagnostics. It is planned that technologies are going to be developed for specific biomarkers testing and new treatment strategies development. These technologies are going to be developed till in vitro diagnostic products and treatment methods.
MD. PhD. Aleksandras Laucevičius. Methods of echocardiography; Diagnosis of heart failure; Treatment of acute myocardial infarction and complex cardiac arrhythmias.
MD. PhD. Augustas Pivoriūnas. Stem cells biology; Tissue engineering; Regenerative medicine; Fundamental and applied stem cells secretome research.
Prof. PhD. Ali Mobasheri. Cartilage biology; Ion channel physiology; Biomarkers of osteoarthritis.
MD. PhD. Eiva Bernotienė. Mesenchymal stem cells and tissue engineering in vitro; Tissue regeneration research; Cartilage and other joint tissues; Heart conduction system; Inflammation; Rheumatic diseases.
Prof. PhD. Vladas Algirdas Bumelis. Research of recombinant proteins renaturation, stability and chemical modification processes; Research of chromatografic processes of recombinant proteins for pharmaceutical purpose; Proteins renaturation-denaturation processes analysis; Physicochemical and biological internals analysis.
MD, PhD, DSc Alexej Verkhratsky. Regulation of neuronal endoplasmic reticulum calcium stores by intraluminal calcium; Cellular neurophysiology; The mechanisms of inter‐ and intracellular signalling in the CNS, being focused on two main types of neural cells, on neurones and neuroglia.
MD. PhD. Mykolas Mauricas. Biomedicine, immunology, biotechnology, stem cells and cytokinetics research, regenerative medicine; Immunoglobulins structure and apply research; Hybridomes and monoclonal antibodies technology, monoclonal and polyclonal antibodies apply in immunoanalysis; Recombinant protein production technologies development and control standardization, functions in vivo and in vitro analysis; Cytokines immunomodulating and mechanisms of signal transmission properties research in cells cultures.